Subtype-Specific Regulation of P2X3 and P2X2/3 Receptors by Phosphoinositides in Peripheral Nociceptors
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چکیده
منابع مشابه
Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors
BACKGROUND P2X3 and P2X2/3 purinergic receptor-channels, expressed in primary sensory neurons that mediate nociception, have been implicated in neuropathic and inflammatory pain responses. The phospholipids phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3) are involved in functional modulation of several types of ion channels. We report here eviden...
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ژورنال
عنوان ژورنال: Molecular Pain
سال: 2009
ISSN: 1744-8069,1744-8069
DOI: 10.1186/1744-8069-5-47